Three Cases of Didelphys Uterus, Including Uterus Didelphys with Obstructed Hemivagina and Ipsilateral Renal Agenesis (OHVIRA Syndrome) AKA Herlyn-Werner-Wunderlich Syndrome), with a Systematic Review

Abstract

Background: Herlyn-Werner-Wunderlich (HWW) syndrome also known as obstructed hemivagina ipsilateral renal agenesis (OHVIRA) is characterized by the presence of a didelphys uterus, obstructed hemivagina and ipsilateral renal agenesis. OHVIRA most commonly presents with symptoms of menarche pelvic pain, dysmenorrhea and an abdominal mass. Surgical intervention is often required to correct malformations and reduce the incidence of pelvic endometriosis, infection, and adhesions, and infertility for these patients. We present three cases MDA with various presentations and clinical courses.