Cystosarcoma phyllodes malignum: A case report of a successive triple modality treatment

Abstract

This paper reports on a woman with a rapidly growing recurrent cystosarcoma phyllodes malignum after two major attemps of surgery. In this situation, neo-adjuvant hyperfractionated radiotherapy, superficial hyperthermia and ifosfamide were administered. Toxicity was mild. Resection of the tumour bed revealed a pathologically complete response with an actual disease free follow-up of 48 months.