Human papillomavirus genotyping using archival vulval dysplastic or neoplastic biopsy tissues: Comparison between the INNO-LiPA and linear array assays

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Abstract

The Roche Linear Array (LA) and Innogenetics INNO-LlPA human papillomavirus (HPV) genotyping assays were compared for paraffin-embedded vulval tissues. The LA detected ampllfiable DNA in 28 (57%) out of 49 biopsy specimens, 20 (40%) being HPV genotyped, compared to 49 (100%) and 41 (83%), respectively, detected by the INNO-LiPA. The INNO-LiPA provides greater sensitivity for HPV genotyping in archival tissue. Copyright © 2010, American Society for Microbiology. All Rights Reserved.

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Tan, S. E., Garland, S. M., Rumbold, A. R., & Tabrizi, S. N. (2010). Human papillomavirus genotyping using archival vulval dysplastic or neoplastic biopsy tissues: Comparison between the INNO-LiPA and linear array assays. Journal of Clinical Microbiology, 48(4), 1458–1460. https://doi.org/10.1128/JCM.02311-09

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