Development of novel pyridine-based agrochemicals: A review

Abstract

Pyridine-based agrochemical products have become the most commercially successful in the 21st century. About half of the agrochemicals with pyridine scaffold were released, registered or invented only in the current millennium. Some of them have a unique structure and previously unknown modes of action. The literature provides examples of the use of the pyridine ring in pesticides for reducing the dosage of the active ingredient, hence to take care of the environment due to their increased efficacy, overcoming the pest resistance, and also makes it possible to create patentable structures by dodging the parent patent, which sometimes leads to a change in the spectrum of activity of the compounds. The newest 13 substances registered by the ISO from January 2021 to June 2024, and not reviewed previously are considered.