Biological Activities of Diterpenoids Isolated from Anatolian Lamiaceae Plants II

Abstract

In this review article, biological activity studies on diterpenoids isolated from Lamiaceae family plants in Türkiye were updated. The studies conducted in the past twenty years (between 2006-2025) were examined, and it was observed that mainly cytotoxic and acetylcholinesterase and butyrylcholinesterase inhibitory activity tests were carried out on diterpenoids, obtained from the Lamiaceae family plants. However, despite the decreasing number of studies, antibacterial, antifungal, cytotoxic, antitumor, cardiovascular, antiviral, antiplasmodial, and insecticidal activities have been investigated. In this review article, 34 abietane diterpenoids from Salvia species, 13 kaurane diterpenoids from Sideritis species, and 3 labdane, and 1 pimarane diterpenoids were isolated from different sources, and their biological activities data were reported.