A new biflavonoid glycoside from the leaves of ziziphus mucronata willd. (rhamnaceae)

Abstract

A new compound was isolated from the n-butanol fraction of the crude methanol extract of the leaves of Ziziphus mucronata, a plant that is widely used in ethnomedicine to treat inflammation, diarrhoea, tumour, cough, sores, asthma, measles, fever, infections and urinary problems, amongst numerous indications. The isolation of the compound was carried out by a combination of silica gel column and sephadex gel filtration chromatography and the structure was elucidated with the help of UV, IR, and 1D, 2D-1H and13C NMR spectroscopic analysis. The compound, a glycoside biflavonoid, was established as bis (quercetin 3-O-β-D-glucopyranoside). The compound might be responsible for some of the observed biological activities of the plant Ziziphus mucronata.