Synchronous columnar cell variant of papillary thyroid carcinoma with invasive breast carcinoma

Abstract

Synchronous or metachronous associations of multiple malignancies are seen commonly in syndromic cases. Double malignancies with thyroid carcinomas are common with papillary thyroid carcinoma (PTC) than with other differentiated thyroid cancers. The presence of double malignancy should be ruled out before treatment as it may need different and multiple treatment modalities. We report a case of a columnar cell variant of PTC with invasive breast carcinoma in 56-year-old female patient. The columnar cell variant of PTC is rare and show inconspicous classical nuclear features of conventional PTC.