Testosterone Deficiency with Erectile Dysfunction in Mongolian Men

Abstract

PURPOSE: To detect the testosterone deficiency syndrome in Mongolian men over 40 years old with erectile dysfunction (ED).$\$n$\$nMATERIALS AND METHODS: Total of 309 males over 40 years of age who received medical care at the ADAM Urology and Andrology Clinic from 2010 to 2011 were included in this study. An approval from the Ethics Committee of the Ministry of Health of Mongolia was obtained, and each study participant signed a consent form at the beginning of the study. The participants were assigned to either an ED group or a control group, depending on the results of the international index of erectile function (IIEF)-5 questionnaire. The ED group was further divided into three groups (moderate, severe, and very severe) based on the level of ED. The total testosterone (TT) levels were determined in the blood serum using a competitive enzyme-linked immunesorbent assay (ELISA) analytical system UBI Magiwel™ Testosterone Quantitative test, and free testosterone (FT) calculated as described by the Vermeulen calculation. Test samples were collected between 8:00 and 11:00 am in the mornings and testosterone deficiency syndrome was diagnosed based on the International Society for the Study of the Aging Male guidelines, particularly, if TT was ≤3.46 ng/ml or free testosterone FT was ≤0.072 ng/ml.$\$n$\$nRESULTS: ED of moderate, severe, and very severe levels was diagnosed in 199 (64.41{%}) out of 309 participants. There was an inverse relationship between the main IIEF-5 score and age (r=-0.380, p{