Modification of near-infrared cyanine dyes by serum albumin protein

24Citations
Citations of this article
23Readers
Mendeley users who have this article in their library.

Abstract

The time-dependent nature of the complexes of IR806 dye and other similar near-infrared cyanine dyes in human serum albumin (HSA) have been studied by employing absorption, emission and time-correlated single photon counting techniques. The complex formation of IR806 with HSA modifies the native structure of IR806, resulting in time-dependent changes in its optical properties. The modification process of the dye and its complex formation with HSA is very slow and takes about 90 min. The process of the formation of the new complex is irreversible and totally controlled by the initial complex of IR806 and HSA. As far as we know, this new property of cyanine dyes has not been reported before. These properties are very important for near-infrared fluorescence imaging. © The Royal Society of Chemistry and Owner Societies 2011.

References Powered by Scopus

Solvatochromic dyes as solvent polarity indicators

4974Citations
N/AReaders
Get full text

Atomic structure and chemistry of human serum albumin

3697Citations
N/AReaders
Get full text

Fluorescence molecular tomography resolves protease activity in vivo

829Citations
N/AReaders
Get full text

Cited by Powered by Scopus

Polymethine dyes as spectral-fluorescent probes for biomacromolecules

113Citations
N/AReaders
Get full text

On the Mechanisms of Uptake of Tumor-Seeking Cyanine Dyes

92Citations
N/AReaders
Get full text

Recent advances in the development of synthetic chemical probes for glycosidase enzymes

69Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Awasthi, K., & Nishimura, G. (2011). Modification of near-infrared cyanine dyes by serum albumin protein. Photochemical and Photobiological Sciences, 10(4), 461–463. https://doi.org/10.1039/c0pp00271b

Readers over time

‘11‘12‘14‘15‘17‘18‘19‘20‘21‘22‘24‘2502468

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 11

73%

Professor / Associate Prof. 2

13%

Researcher 2

13%

Readers' Discipline

Tooltip

Chemistry 9

56%

Agricultural and Biological Sciences 4

25%

Medicine and Dentistry 2

13%

Chemical Engineering 1

6%

Save time finding and organizing research with Mendeley

Sign up for free
0