Novel Bioactive Compound Production by Microbial Biota: Potential Antimicrobials

Abstract

Man is always trying to make his life easier and accomplished. He has faced mass destruction in historydue to epidemics like small pox, malaria and plague. In order to combat diseases, exploration of man ledhim to search for causative agents and their control. A time reached when it was found that microbes arethemselves a source of potent metabolites which have proved to be effective as drugs and medicinesshowing great antibiotic activity. It is necessary to find out new sources for potential new antimicrobialcompounds. Several hundred important compounds have been isolated which have antibiotic activitiesand diverse chemical nature. But these compounds should have minimum toxicity to be useful clinically.Because of the increasing resistance of pathogens, there was a never ending desire and need to searchfor more. Bioactive Compounds have been extracted from microbes which are produced as secondarymetabolites. Day by day, new compounds are being discovered giving a hope of golden future of drugindustry. The current article emphasizes the importance and need to search for new bioactive compoundsto overcome infections caused by multiple drug resistant (MDR) and biofilm forming pathogensirrespective of the previously present knowledge.