Influence of hormonal menopausal changes on the clinical course of psoriasis. Psoriasis and menopause: part 2

Abstract

Sex hormones are known to influence cutaneous physiology in many different ways. Although hormonal balance is probably best known for its commitment in skin ageing, there is a growing body of evidence that both estrogens and androgens may also have a significant effect on immune response. Modification of the natural course of many chronic inflammatory disorders during pregnancy, menstrual cycle or perimenopausal period suggest a hormonally induced shift in immune balance. In this paper we present and discuss current medical literature about epidemiology and course of psoriasis in the postmenopausa l period with respect to hormonal changes.