A novel one-pot, three-component synthesis of alkyl 6-aryl-3- methylpyridazine-4-carboxylates in water

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Abstract

A series of new alkyl 6-aryl-3-methylpyridazine-4-carboxylates were efficiently synthesized by a three-component reaction of β-ketoesters with arylglyoxals in the presence of hydrazine hydrate in water at room temperature. © ARKAT USA, Inc.

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Rimaz, M., & Khalafy, J. (2010). A novel one-pot, three-component synthesis of alkyl 6-aryl-3- methylpyridazine-4-carboxylates in water. Arkivoc, 2010(2), 110–117. https://doi.org/10.3998/ark.5550190.0011.208

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