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N-H spin-spin couplings: Probing hydrogen bonds in proteins

Angewandte Chemie - International Edition (2013) 52(12) 3525-3528
DOI: 10.1002/anie.201209641
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Abstract

Sensitive information: Hydrogen bonds stabilize protein structures and are critical for many chemical and biological phenomena. NMR studies found that the one-bond 1H-15N scalar coupling constant is increased by up to 1.6 Hz when a hydrogen bond is formed. These coupling constants therefore provide a sensitive tool for studying protein structure. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Xiang, S. Q., Narayanan, R. L., Becker, S., & Zweckstetter, M. (2013). N-H spin-spin couplings: Probing hydrogen bonds in proteins. Angewandte Chemie - International Edition, 52(12), 3525–3528. https://doi.org/10.1002/anie.201209641

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