Enantioselectivity for catalytic cyclopropanation with diazomalonates

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Abstract

The use of chiral azetidinone-ligated dirhodium(II) catalysts activates dinitrogen extrusion from diazomalonates and provides access to cyclopropanation products with selectivities as high as 40-50% ee.

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Doyle, M. P., & Hu, W. (2003). Enantioselectivity for catalytic cyclopropanation with diazomalonates. Arkivoc, 2003(7), 15–22. https://doi.org/10.3998/ark.5550190.0004.703

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