Agr/sarA: Molecular switches of biofilm regulation in Staphylococcus aureus

Abstract

Biofilms are commonly referred to as extra cellular matrices or extra polymeric structures composed of bio molecules and are known for their complexity. They confer the pathogen with a variety of functions that make them resilient and virulent. The current mini review attempts to highlight the significance of agr/sarA regulators and their role as molecular switches in the formation and dispersal of Staphylococcus biofilms.