Simple synthesis of 3-acyl-5-alkyl(aryl)isoxazoles from terminal alkynes and nitrates of alkaline metals or ammonium

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Abstract

A simple and general synthesis of 3-acyl-5-alkyl(axyl)isoxazoles by reaction of terminal alkynes with nitrates in acetic acid in the presence of SO3 or alkaline salts is described. © Central European Science Journals. All rights reserved.

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Rogachev, V. O., Filimonov, V. D., Kulmanakova, J. Y., Yusubov, M. S., & Bender, W. (2005). Simple synthesis of 3-acyl-5-alkyl(aryl)isoxazoles from terminal alkynes and nitrates of alkaline metals or ammonium. Central European Journal of Chemistry, 3(3), 370–376. https://doi.org/10.2478/bf02479268

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