COMPARISION OF CURCUMIN NANOEMULSION DROPS SIZE BETWEEN HOMINIZATION AND ULTRASONICATION SUPPORTING

Abstract

In this paper, curcumin nano-emulsions were successfully prepared by combining hominization and ultra-sonication methods which have been mentioned. The optimal conditions for the hominization method have been established as follows: 3% emulsifier concentration, 20,000 rpm of capacity in 60 minutes, the average size of nano drops was 78 nm. Meanwhile, the optimal conditions of the ultrasonic method are also constructed as follows: 2% emulsifier concentration, 450 w/g of ultrasonic power, 20 kHz frequency, the average size of the droplet was 58 nm. Nano-emulsion system has been stable after 4 months of cold storage.