The pharmacological assessment of single drugs and drug combinations in exercise induced asthma

Abstract

The relative effectiveness of ephedrine, theophylline, hydroxyzine and their combinations in relieving cycloergometer exercise induced asthma were studied in 16 children and adolescents. Ephedrine had no effect on post exercise asthma, hydroxyzine had a weak effect on hastening recovery, while theophylline modified the post exercise response significantly. The 3 drugs together produced an additive effect superior to that of theophylline alone.