A Review of Colitis Ulcers in the Gastrointestinal Tract

Abstract

Colitis ulcer disease is a chronic disorder that affects the gastrointestinal tract. The disease is characterized by abnormal inflammation of the inner surface of the rectum and intestine, which makes up most of the length of the large intestine. Inflammation usually causes open sores (ulcers) in the large intestine. Doctors still do not know exactly what causes ulcerative colitis. Ulcerative colitis is an inflammatory bowel disease, but genetics appear to play an important role. Family history is seen in many patients with ulcerative colitis. In fact, having a relative with ulcerative colitis is the biggest risk factor for the disease, meaning you may inherit the genetic cause of ulcerative colitis. In addition, some environmental factors are involved in the immune system attacking the colon and developing ulcerative colitis. Families with ulcerative colitis share some of the genes that appear to be linked to the disease. Note that several genetic changes may play a role in the development of ulcerative colitis. Genes may stimulate ulcerative colitis by altering the immune system response or disrupting the protective barrier of the intestinal wall.