Abstract
Conrad et al. (Reports, 10 August 2012, p. 742) reported a doubling of RNA polymerase II (Pol II) occupancy at X-linked promoters to support 5′ recruitment as the key mechanism for dosage compensation in Drosophila. However, they employed an erroneous data-processing step, overestimating Pol II differences. Reanalysis of the data fails to support the authors' model for dosage compensation.
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CITATION STYLE
Ferrari, F., Jung, Y. L., Kharchenko, P. V., Plachetka, A., Alekseyenko, A. A., Kuroda, M. I., & Park, P. J. (2013, April 19). Comment on “Drosophila dosage compensation involves enhanced Pol II recruitment to male X-linked promoters.” Science. American Association for the Advancement of Science. https://doi.org/10.1126/science.1231815
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