Low-level laser therapy and Calendula officinalis in repairing diabetic foot ulcers

Citations of this article
Mendeley users who have this article in their library.


Objective: To evaluate the effects of low-level laser therapy isolated and associated with Calendula officinalis oil in treating diabetic foot ulcers. Method: An experimental, randomized, controlled, prospective, interventional clinical case study using a quantitative approach. The sample consisted of 32 diabetic patients of both genders. Participants were randomly divided into four groups. Doppler Ultrasound evaluation of the Ankle-Brachial Index, brief pain inventory and analog pain scale were performed at baseline and after 30 days. Results: Reduced pain was observed in the Low-level laser therapy and Low-level laser therapy associated with Essential Fatty Acids groups (p < 0.01). Regarding the Ankle-Brachial Index and Doppler Ultrasound, all groups remained stable. By analyzing lesion area reduction, Low-level laser therapy associated with Essential fatty acids group showed a significance of p=0.0032, and the Low-level laser therapy group showed p=0.0428. Conclusion: Low-level laser therapy, performed alone or associated with the Calendula officinalis oil was effective in relieving pain and accelerating the tissue repair process of diabetic foot.




de Carvalho, A. F. M., Feitosa, M. C. P., Coelho, N. P. M. de F., Rebêlo, V. C. N., de Castro, J. G., de Sousa, P. R. G., … Arisawa, E. A. L. S. (2016). Low-level laser therapy and Calendula officinalis in repairing diabetic foot ulcers. Revista Da Escola de Enfermagem, 50(4), 626–632. https://doi.org/10.1590/S0080-623420160000500013

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free