Infections in urinary tract of patients with haematological malignancies undergoing antineoplastic therapy

Abstract

The treatment of the malignant diseases requires the use of combination chemotherapy in multiple cycles administered to achieve adequate tumor cell kill without life-threatening toxicity or the development of tumor cell resistance. Patients and methods:72 patients (48 women and 24 men, median age-47, from 24 to 71years with urinary tract infections (UTI), hospitalized in the Clinic of Hematology for the period January 2006-May 2008. Urinalysis: microscopic examination-white blood cells (WBC), bacteria; urine culture; sensitivities of culture. Blood tests: urea (kinetic UV test), creatinin (Jaffe kinetic), CRP (immunoturbidimetric method), blood culture, sensitivities of culture. Results and conclusions:The urinary tract infections are a common complication during the combination chemotherapy patients with hematological malignancies. For the period 2006-2008, 72 patients undergoing combination chemotherapy were diagnosed with UTI.