(E)-1-(2-Aminophenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one

Abstract

In the asymmetric unit of the title chalcone derivative, C 18H 19NO 4, there are three crystallographically independent molecules (molecules A, B and C). In molecule A, the dihedral angle between two benzene rings is 12.22 (10)° and the plane of the central prop-2-en-1-one unit makes dihedral angles of 11.02 (13) and 2.64 (12)° with the two adjacent benzene rings. The corresponding angles in molecule B are 12.35 (10), 18.78 (12) and 7.29 (12)°, respectively, and those in molecule C are 15.40 (10), 15.62 (3) and 3.19 (13)°. In each molecule, an intramolecular N - H⋯O hydrogen bond generates an S(6) ring motif. In the crystal structure, the molecules B are linked by intermolecular N - H⋯O hydrogen bonds into a zigzag chain along the c axis, while the molecules A and C are linked together via an N - H⋯O hydrogen bond into a dimer. Adjacent dimers are further connected by N - H⋯N hydrogen bonds into a threedimensional network. Weak C - H⋯O and C - H⋯π interactions are also observed.