Synthesis and Inhibitory Activity of Schiff base Surfactants Derived from Tannic Acid against Bacteria and Fungi

Abstract

ASERIES of tannic acid Schiff base surfactants were synthesized and their structures were elucidated using microelemental analysis, FTIR and 1H-NMR data. The molecular weights were determined using viscosity measurements and gel permeation chromatography. The surface activities of the surfactants were determined by surface tension measurements. The antimicrobial activity and minimum inhibitory concentrations were evaluated by disk diffusion assay against gram-positive, gram-negative bacteria and fungi. The antimicrobial data disclosed that the tested compounds demonstrated moderate to excellent microbial inhibitions. Compounds TGB1 showed high potency against the tested strains.