Changes in quality of life into adulthood after very preterm birth and/or very low birth weight in the Netherlands

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Abstract

Background: It is important to know the impact of Very Preterm (VP) birth or Very Low Birth Weight (VLBW). The purpose of this study is to evaluate changes in Health-Related Quality of Life (HRQoL) of adults born VP or with a VLBW, between age 19 and age 28. Methods: The 1983 nationwide Dutch Project On Preterm and Small for gestational age infants (POPS) cohort of 1338 VP (gestational age <32 weeks) or VLBW (<1500 g) infants, was contacted to complete online questionnaires at age 28. In total, 33.8% of eligible participants completed the Health Utilities Index (HUI3), the London Handicap Scale (LHS) and the WHOQoL-BREF. Multiple imputation was applied to correct for missing data and non-response. Results: The mean HUI3 and LHS scores did not change significantly from age 19 to age 28. However, after multiple imputation, a significant, though not clinically relevant, increase of 0.02 on the overall HUI3 score was found. The mean HRQoL score measured with the HUI3 increased from 0.83 at age 19 to 0.85 at age 28. The lowest score on the WHOQoL was the psychological domain (74.4). Conclusions: Overall, no important changes in HRQoL between age 19 and age 28 were found in the POPS cohort. Psychological and emotional problems stand out, from which recommendation for interventions could be derived. © 2013 van Lunenburg et al.; licensee BioMed Central Ltd.

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van Lunenburg, A., van der Pal, S. M., van Dommelen, P., van der Pal de Bruin, K. M., Bennebroek Gravenhorst, J., & Verrips, G. H. W. (2013). Changes in quality of life into adulthood after very preterm birth and/or very low birth weight in the Netherlands. Health and Quality of Life Outcomes, 11(1). https://doi.org/10.1186/1477-7525-11-51

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