Hereditary bleeding disorder, factor ix deficiency in females: A case series

Abstract

Introduction: Hemophilia is uncommon in females and there is little knowledge about the clinical manifestation. Case presentation: We report here an unusual case of three hemophilic females diagnosed as factor IX deficient. Normal reports of ultrasonography (USG) and relevant endocrine investigations conducted in two adult females ruled out any usual gynecological and endocrinal causes of bleeding. Complete coagulation profiles were conducted and diagnosed these female bleeders to be hemophiliacs suffering from factor IX deficiency. Conclusion: Females presenting with menorrhagia and bleeding from other sites without any discernable cause require proper evaluation for congenital coagulation disorders. In the present case series, females are diagnosed factor IX deficient (Hemophilia B). © 2009 Mishra; licensee Cases Network Ltd.