BK-Related Polyomavirus Vasculopathy in a Renal-Transplant Recipient

Abstract

Human polyomaviruses include JC virus, which can cause progressive multifocal leukoencephalopathy, and BK virus, which can cause severe allograft dysfunction in renal-transplant recipients. This report describes a renal-transplant recipient in whom a disseminated BK virus infection with vascular tropism developed, resulting in systemic vasculopathy, the capillary leak syndrome, and death.