Genetic modeling of primary tooth emergence: A study of Australian twins

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The aim of this study was to quantify contributions of genetic and environmental factors to variation in timing of emergence of the primary teeth in a sample of monozygotic and dizygotic twins, using univariate model-fitting approaches. The sample comprised 94 pairs of monozygotic twins and 125 pairs of dizygous twins, all of European ancestry, aged from 2-6 years. Tooth emergence timing was based on parental report, with a subset of data validated by clinical assessment. Heritability estimates for tooth emergence timing were generally high, around 90%, however estimates for the lower right lateral incisor and the lower canines were around 50%. These findings confirm a strong genetic influence on observed variation in the timing of emergence of the human primary teeth.

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Bockmann, M. R., Hughes, T. E., & Townsend, G. C. (2010). Genetic modeling of primary tooth emergence: A study of Australian twins. Twin Research and Human Genetics, 13(6), 573–581.

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