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Utility of recombinant fragment C for assessment of anti-tetanus antibodies in plasma

Diagnostic Microbiology and Infectious Disease (2015) 82(1) 11-13
DOI: 10.1016/j.diagmicrobio.2015.01.016
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Abstract

Anti-tetanus antibodies in biological samples are typically detected using an enzyme-linked immunosorbent assay based on toxoided tetanus neurotoxin as antigen. We demonstrate that recombinantly produced fragment C of the toxin heavy chain is an effective alternative antigen for assessment of tetanus-immune status in plasma samples.

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Ramakrishnan, G., Pedersen, K., Guenette, D., Sink, J., Haque, R., Petri, W. A., … Gilchrist, C. A. (2015). Utility of recombinant fragment C for assessment of anti-tetanus antibodies in plasma. Diagnostic Microbiology and Infectious Disease, 82(1), 11–13. https://doi.org/10.1016/j.diagmicrobio.2015.01.016

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