Antimicrobial activity of Nepeta isolates

Abstract

Iridodial β-monoenol acetate and actinidine, constituents of Nepeta leucophylla Benth and N. clarkei Benth respectively were investigated for their in vitro antimicrobial activity against 11 fungi and 8 bacteria. Both compounds demonstrated broad spectrum antifungal activity. Iridodial β-monoenol acetate showed remarkable activity against Penicillium citrinum and Aspergillus fumigates, while actinidine was most active against A. ochraceus. Both were moderately active against Bacillus anthracis and Streptococcus pyrogenes.