A new spatane diterpenoid from the cultured soft coral sinularia leptoclados

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Abstract

A new spatane diterpenoid, leptoclalin A (1), along with two previously reported known norcembranoid diterpenes (2 and 3), were isolated from a cultured soft coral Sinularia leptoclados. The structures were determined by extensive spectroscopic analyses and by comparison with the spectral data of related known compounds. Metabolite 1 is rarely found in spatane skeletons reported from soft corals. In addition, compound 1 exhibited weak cytotoxicity towards human tumor cell lines T-47 D and K-562. © 2013 by the authors.

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Tsai, T. C., Wu, Y. J., Su, J. H., Lin, W. T., & Lin, Y. S. (2013). A new spatane diterpenoid from the cultured soft coral sinularia leptoclados. Marine Drugs, 11(1), 114–123. https://doi.org/10.3390/md11010114

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