PRKCD (protein kinase C, delta)

  • Malavez Y
  • Gonzalez-Mejia M
  • Doseff A
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Abstract

The protein kinase C (PKC) family consists of 11 isoenzymes that, due to structural and enzymatic differences, can be subdivided into three groups: The Ca(2+)-dependent, diacylglycerol (DAG)-activated cPKCs (conventional PKCs: alpha, beta 1, beta 2, gamma); the Ca(2+)- independent, DAG-activated nPKCs (novel PKCs: delta, epsilon, eta, theta, mu), and the Ca(2+)-dependent, DAG non-responsive aPKCs (atypical PKCs: zeta, lambda/iota). PKC mu is a novel PKC, but with some special structural and enzymatic properties.

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Malavez, Y., Gonzalez-Mejia, M., & Doseff, A. (2011). PRKCD (protein kinase C, delta). Atlas of Genetics and Cytogenetics in Oncology and Haematology, (p. 75-77). https://doi.org/10.4267/2042/44382

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