In vitro antioxidant effect of ethanol extract from pennisetum purpureum

Abstract

In vitro antioxidant effect of 50% ethanol extract from Napier grass (Penninsetum purpureum) was investigated. The yield and polyphenol content of the Napier grass extract were 6.3±0.35% and 79.6±3.65 µg gallic acid equivalents/mg-extract, respectively. Antioxidant ability of the Napier grass extract such as fee radical and cation radical scavenging activities, reducing power, nitrite scavenging activity, and lipid peroxidation inhibitory activity proportionally increased as concentration of the extract increased. EC50 values of the Napier grass extract for free radical scavenging, cation radical scavenging, reducing power, and nitrite scavenging were 1,930.0, 350.0, 840.0, and 1,470.0 µg/mL, respectively. In the presence of 85.0 µg/mL of the Napier grass extract, lipid peroxidation was potently inhibited by 74.6%.