Nomifensine in Parkinsonism

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Abstract

Nomifensine, a tetrahydroisoquinoline antidepressant which facilitates dopaminergic and noradrenergic transmission, was studied in 28 Parkinsonism patients most of whom were also receiving conventional medications. Double-blind evaluations revealed a moderate therapeutic action at a mean dose level of 150 mg daily. Adverse reactions were encountered, similar to those induced by levodopa.

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APA

Teychenne, P. F., Park, D. M., Findley, L. J., Rose, F. C., & Calne, D. B. (1976). Nomifensine in Parkinsonism. Journal of Neurology, Neurosurgery and Psychiatry, 39(12), 1219–1221. https://doi.org/10.1136/jnnp.39.12.1219

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