A Fear Memory Engram and Its Plasticity in the Hypothalamic Oxytocin System

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Abstract

Hasan et al. developed a novel genetic method, vGATE, to tag a context-specific fear memory engram in the hypothalamic oxytocin system that participates in rapid unfreezing, extinction, and enhanced glutamatergic transmission.

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Hasan, M. T., Althammer, F., Silva da Gouveia, M., Goyon, S., Eliava, M., Lefevre, A., … Grinevich, V. (2019). A Fear Memory Engram and Its Plasticity in the Hypothalamic Oxytocin System. Neuron, 103(1), 133-146.e8. https://doi.org/10.1016/j.neuron.2019.04.029

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