Crystal structure of methyl 2-hydroxy-5-[(4-oxo-4,5-dihydro-1,3-thiazol-2-yl)-amino]benzoate

Abstract

The title compound, C11H10N2O4S, crystallized with two independent molecules (A and B) in the asymmetric unit. They differ primarily in the rotational orientation of the five-membered heterocyclic ring. In molecule A this ring is inclined to the benzene ring by 48.17 (8)°, while in molecule B the same dihedral angle is 23.07 (8)°. In each molecule there is an intramolecular O - H⋯O hydrogen bond involving the adjacent hydroxyl group and the ester carbonyl O atom. In the crystal, the A molecules are linked via pairs of N - H⋯N hydrogen bonds, forming inversion dimers. These dimers are linked to the B molecules via N - H.·O, C - H⋯O and C - H⋯ S hydrogen bonds forming corrugated sheets lying parallel to (102).