Removal of Metformin hydrochloride from Aqueous Solutions by using Carboxymethyl cellulose-g-poly(acrylic acid-co-acrylamide) Hydrogel: Adsorption and Thermodynamic Studies

Abstract

The ]Sodium Carboxymethyl Cellulose-grafting-Poly(Acryl Amide-Acrylic Acid) [ hydrogel was synthesized through free radical polymerization method of CMC, AAm, and AAc. Potassium persulfate(KPS) and N, N methylene bis-acrylamide (MBA) were used as initiator and crosslinking agent, respectively. FTIR, XRD, FESEM, and TGA were used to characterize the synthesized hydrogel. The hydrogel was used to remove metformin hydrochloride drug from aqueous solutions. The analysis clarifies the effect of several parameters on the quantity of adsorbate, including pH at a range of (1.2-12), the temperature at a range of (15, 20, 25 and 30°C), equilibrium time (1-240 min), and adsorbate weight at a range of (0.001-0.1 g). It is discovered that as temperature increases and pH decreases, the quantity of adsorbate present decreases. Equilibrium time 120 min. The adsorption isotherm seems to indicate that the adsorption mechanism followed Freundlich and Temkin models. Thermodynamic functions were measured, and it was discovered that the adsorption mechanism is exothermic and spontaneous.