A new and efficient catalytic isomerization of cis- and trans-epoxides

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Abstract

We report new ruthenium-catalyzed cis-trans isomerization of various functionalized epoxides. Enantiospecific isomerization of chiral epoxides is achieved without loss of enantiopurity, and epimerization occurs only at the epoxide carbon of the activating group. © 2003 Elsevier Science Ltd. All rights reserved.

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Lo, C. Y., Pal, S., Odedra, A., & Liu, R. S. (2003). A new and efficient catalytic isomerization of cis- and trans-epoxides. Tetrahedron Letters, 44(15), 3143–3146. https://doi.org/10.1016/S0040-4039(03)00465-9

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