Abstract
The mitotic spindle is the apparatus upon which chromosomes are segregated during cell division. We have discovered new roles for two members of the NIMA-related kinase (NEK) family in different molecular processes of spindle assembly. Moreover, loss of these proteins leads to segregation errors that drive cancer progression.
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Prosser, S. L., O’Regan, L., & Fry, A. M. (2016). Novel insights into the mechanisms of mitotic spindle assembly by NEK kinases. Molecular and Cellular Oncology, 3(3). https://doi.org/10.1080/23723556.2015.1062952
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