The effects of reactive oxygen species in the process of skin photoaging

Abstract

Skin is the largest organ of human body and it protects the organism from external stimuli. Skin will age as the organism ages in normal circumstances. Skin photoaging refers to the accumulation of ultraviolet radiation due to long-term exposure to sunlight, which results in the premature aging of skin, wrinkles, pigmentation, skin laxity, and other signs of aging. The increase in the level of reactive oxygen species (ROS) induced by ultraviolet radiation, which causes the oxidation of cells, proteins, lipids, and other components, is an important cause of accelerated photoaging of skin. For this reason, the skin's antioxidant system will further play an antioxidant role to reduce oxidative damage by inhibiting ROS production, breaking down ROS, and degrading oxides. Therefore, it is important to understand the mechanism of skin damage caused by Ultraviolet radiation, the effects of reactive oxygen species and how the body's antioxidant system exerts its antioxidant effect. This will not only deepen the understanding of skin photoaging but also provide a scientific basis for the research on how to prevent and treat photoaging.