Overview of transfusion reactions in patients with incompatible crossmatch at Sanglah General Hospital, Denpasar, Bali, Indonesia

Abstract

Background: Transfusion reaction is a side effect of giving complete blood or one ofthe components. They vary in severity, ranging from reactions that can occur during a transfusion (acute transfusion reactions) or reactions occurring days to weeks later (delayed transfusion reactions) and can be immunological and non-immunological. This study investigated the description of transfusion reactions in patients who receivedblood with incompatible crossmatch results at Sanglah General Hospital. Methods: This research is a descriptive study with a cross-sectional approach. Several parameters were assessed in this study to determine the transfusion reaction in patients who receive blood with incompatible crossmatch. Data were analyzed using SPSS version 20 for Windows. Results: In this study, from 72 patients who received incompatible blood, 75.0% were found for women and 25.0% for male patients, most of whom were aged 41-65 years (65.0%). Most blood type is blood type O (52.0%). In this study, 6 patients (8.3%) got transfusion reactions such as fever accompanied by chills, urticaria, hypotension, and shortness of breath. Conclusions: Incompatible crossmatch blood administration can be given. If a reaction is given to a crossmatch transfusion that is not suitable, symptomatic therapy can be given because the response provided is only acute and mild.