Characterization of an x-ray source with a partitioned diamond-tungsten target for electronic brachytherapy with 3D beam directionality

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Abstract

The Sculptura™ is a new high-dose-rate electronic brachytherapy system developed by Sensus Healthcare. By combining a steerable electron beam with a partitioned diamond-tungsten x-ray target, the x-ray source of the Sculptura™ is capable of producing highly anisotropic dose distributions, thus achieving true 3D beam directionality. This article reports the spectral and dosimetric characterization of the Sculptura™ x-ray source through a combination of measurements and Monte Carlo simulations for operating points between 50-100 kV. Excellent agreement (∼5% discrepancy) between the simulations and measurements was obtained for in-air dose rate characterization. The validated simulations were then used to calculate the dose distribution in water. Dose rates of >2 cGy/min/μA can be produced at 100 kV, thus delivering 10 Gy in 1 min for typical operating conditions. The dose distributions are sharply peaked, with a full-width at half-maximum azimuth of about 100 .

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Badali, D. S., Plateau, G. R., Ellenor, C. W., Ku, C. Y., Vatahov, P., Esterline, J., … Funk, T. (2019). Characterization of an x-ray source with a partitioned diamond-tungsten target for electronic brachytherapy with 3D beam directionality. Physics in Medicine and Biology, 64(24). https://doi.org/10.1088/1361-6560/ab5130

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