Abstract
The spindle assembly checkpoint arrests mitotic cells by preventing degradation of cyclin B1 by the anaphasepromoting complex/cyclosome, but some cells evade this checkpoint and slip out of mitosis. Balachandran et al. (2016. J. Cell Biol. http ://dx .doi .org /10 .1083 /jcb .201601083) show that the E3 ligase CRL2ZYG11 degrades cyclin B1, allowing mitotic slippage.
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CITATION STYLE
APA
Brandeis, M. (2016). Slip slidin’ away of mitosis with CRL2Zyg11. Journal of Cell Biology, 215(2), 143–145. https://doi.org/10.1083/jcb.201609086
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