Effect of a combination of antimicrobial agents for the treatment of respiratory disease in cattle

Abstract

Clinical effect of the administration of thiamphenicol (TP) and tylosin (TS) on bovine respiratory disease was investigated. Group I (n=64) were administered TP (10 mg/kg) and TS (4 mg/kg), group II (n=26) were given TP (5 mg/kg) and TS (2 mg/kg). For the control, TP group (n=25) were given 20 mg/kg of TP and ampicillin group (n=23) were given 10 mg/kg of ampicillin. As a result, improvement of clinical findings was more rapid and the cure rate was significantly higher in group I compared to those in the other 3 groups. These results showed that a combination therapy with minimal basic doses of TP and TS is very effective for some respiratory diseases in cattle.