Emergence of drug resistant tuberculosis like multi drug resistant tuberculosis (MDR-TB), extensively drug-resistant tuberculosis (XDR-TB) and totally drug resistant tuberculosis (TDR-TB) has created a new challenge to fight against these bad bugs of Mycobacterium tuberculosis. Repurposing and revival of the drugs are the new trends/options to combat these worsen situations of tuberculosis in the antibiotics resistance era or in the situation of global emergency. Bactericidal and synergistic effect of repurposed/revived drugs along with the latest drugs bedaquiline and delamanid used in the treatment of MDR-TB, XDR-TB, and TDR-TB might be the choice for future promising combinatorial chemotherapy against these bad bugs.
CITATION STYLE
Sharma, D., Dhuriya, Y. K., Deo, N., & Bisht, D. (2017). Repurposing and revival of the drugs: A new approach to combat the drug resistant tuberculosis. Frontiers in Microbiology, 8(DEC). https://doi.org/10.3389/fmicb.2017.02452
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