Tolerance of Shore Crabs to Tetrodotoxin and Saxitoxin and Antagonistic Effect of Their Body Fluid against the Toxins

19Citations
Citations of this article
6Readers
Mendeley users who have this article in their library.

Abstract

Lethal effects of tetrodotoxin (TTX) and saxitoxin (STX) on 6 species of nontoxic marine crabs, as well as effects of the toxins on their nerves, were investigated. There was wide variance among species examined for the lethal effect of TTX and STX. The tolerances of nerves are almost compatible to lethal tolerance with the exception of Hemigrapsus sanguineus. This species showed relatively high resistance to TTX, but its nerve was at almost the same level of tolerance as those of other TTX-sensitive crabs. In order to elucidate the mechanism for high TTX-resis-tance in H. sanguineus, nerve tolerance was measured in the presence of its body fluid. The body fluid reduced the effect of TTX on the nerves, while no effect was observed for STX. It is also confirmed that pre-injection of the body fluid of H. sanguineus into a mouse was effective to some extent in protecting the mouse from TTX attack. © 1992, The Japanese Society of Fisheries Science. All rights reserved.

References Powered by Scopus

Chemicals as tools in the study of excitable membranes

723Citations
N/AReaders
Get full text

Interspecies Distribution and Possible Origin of Tetrodotoxin

83Citations
N/AReaders
Get full text

Tetrodotoxin, Tarichatoxin, and Chiriquitoxin: Historical Perspectives

71Citations
N/AReaders
Get full text

Cited by Powered by Scopus

Accumulation of paralytic shellfish poisoning toxins in the edible shore crab Telmessus acutidens

41Citations
N/AReaders
Get full text

Haemolymph protein in xanthid crabs: Its selective binding of saxitoxin and possible role in toxin bioaccumulation

35Citations
N/AReaders
Get full text

Occurrence of tetrodotoxin-binding high molecular weight substances in the body fluid of shore crab (Hemigrapsus sanguineus)

34Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Yamamori, K., Maehara, E., Yamaguchi, S., & Matsui, T. (1992). Tolerance of Shore Crabs to Tetrodotoxin and Saxitoxin and Antagonistic Effect of Their Body Fluid against the Toxins. Nippon Suisan Gakkaishi (Japanese Edition), 58(6), 1157–1162. https://doi.org/10.2331/suisan.58.1157

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 2

67%

Professor / Associate Prof. 1

33%

Readers' Discipline

Tooltip

Agricultural and Biological Sciences 2

100%

Save time finding and organizing research with Mendeley

Sign up for free