oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae

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Abstract

The genes for multidrug efflux pump OqxAB, which is active on fluoroquinolones, were found in human clinical isolates on a plasmid in Escherichia coli and on the chromosome of Klebsiella pneumoniae. IS26-like sequences flanked the plasmid-mediated oqxAB genes, suggesting that they had been mobilized as part of a composite transposon. Copyright © 2009, American Society for Microbiology. All Rights Reserved.

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Hong, B. K., Wang, M., Chi, H. P., Kim, E. C., Jacoby, G. A., & Hooper, D. C. (2009). oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae. Antimicrobial Agents and Chemotherapy, 53(8), 3582–3584. https://doi.org/10.1128/AAC.01574-08

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