Palladium-catalyzed carbonylative suzuki coupling of benzyl halides with potassium aryltrifluoroborates in aqueous media

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Abstract

A general palladium-catalyzed carbonylative cross-coupling reaction of benzyl chlorides with potassium aryltrifluoroborates in water has been developed. Applying this improved methodology 16 different 1,2-diarylethanones have been synthesized in 40-89% yield. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Wu, X. F., Neumann, H., & Beller, M. (2011). Palladium-catalyzed carbonylative suzuki coupling of benzyl halides with potassium aryltrifluoroborates in aqueous media. Advanced Synthesis and Catalysis, 353(5), 788–792. https://doi.org/10.1002/adsc.201000804

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