Myringoplasty with Autologous Platelet Rich Plasma -A Prospective Study

Abstract

Background: The study was conducted to analyse of the effect of autologous Platelet Rich Plasma (PRP) in Myringoplasty. Methods: This prospective study was conducted at Rajah Muthiah Medical college hospital in the department of otorhinolaryngology, from October 2016 to September 2018, among 20 patients who presented to the hospital with symptoms and signs suggestive of chronic otitis media. The management of the disease with myringoplasty using platelet rich plasma was studied and postoperative graft uptake and improvement in hearing were studied. Results: The mean age group was 32.1 years. The graft uptake was successful in all patients in whom platelet rich plasma was used in myringoplasty. There was hearing improvement of at least 10 dB in 85% of the patients. Conclusion: Platelet rich plasma with its various growth factors, has the property of tissue bio stimulation which significantly improves post-operative graft uptake in myringoplasty.