Synthesis of 1H-Indol-3-ylpyrazole derivatives from 1,3,5-triketones and arylhydrazines: One-pot construction of pyrazole and indole rings

Abstract

The reaction of 1,3,5-triketones and arylhydrazines provided indolylpyrazole derivatives in a one-pot reaction in good to moderate yields. Both the pyrazole and indole rings were constructed simultaneously with phenylhydrazine, RCOCH2CO- moiety for the pyrazole and the remaining -CH2COR part for the indole ring.